What are the most common side effects of Wegovy?

The most common side effects of Wegovy are listed below. Tell your health care provider if you have any of these side effects that bother you.

• Nausea/vomiting
• Diarrhea/constipation
• Stomach pain, upset stomach or indigestion, acid reflux
• Headache
• Tiredness
• Dizziness
• Swelling of your stomach area
• Low blood sugar (in people with diabetes)
• Gas or burping
• Stomach flu
• Infection in the nose or throat, sore throat, or common cold symptoms

There may be other side effects of Wegovy that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345. wegovy for sale

What are the serious side effects of Wegovy?

While less common, the most serious side effects of Wegovy are described below, along with what to do if they happen.

Severe Allergic Reactions. Wegovy may cause allergic reactions, which can be serious. Stop using Wegovy and get help right away if you have any of the following symptoms of a serious allergic reaction.

• Breathing problems or wheezing
• Racing heart
• Fever or general ill feeling
• Swollen lymph nodes
• Swelling of the face, lips, mouth, tongue, or throat
• Trouble swallowing or throat tightness
• Itching, skin rash, or pale red bumps on the skin called hives
• Nausea or vomiting
• Dizziness, feeling lightheaded, or fainting
• Stomach cramps
• Joint pain

Thyroid Tumors. Wegovy may cause you to develop thyroid tumors. Some of these tumors could be cancerous. Tell your health care provider right away if you notice any of the following symptoms of a thyroid tumor.

• Swelling or a lump in your neck
• Hoarseness
• Trouble swallowing
• Trouble breathing

Pancreatitis. Wegovy may cause inflammation of the pancreas, which is called pancreatitis. Stop using Wegovy and call your health care provider right away if you have symptoms of pancreatitis, including vomiting or severe pain in the upper part of your belly that travels to your back.

Gallbladder Problems. Using Wegovy can cause gallbladder problems, including cholecystitis and cholelithiasis (also known as gallstones). Call your health care provider right away if you have any of the following symptoms.

• Your skin or the whites of your eyes turning yellowish in color (also called jaundice)
• Fever
• Pain in your upper stomach area
• Stool (poop) that is clay-colored

Low Blood Sugar (Hypoglycemia). Wegovy can cause low blood sugar, especially when used with insulin or other medicines that increase your insulin levels. Hypoglycemia can be serious and may lead to death. Your dose of insulin or other diabetes medicine may need to be lowered to decrease your risk of low blood sugar. Do not use Wegovy and call your health care provider right away if you have any of the following symptoms of hypoglycemia.

• Headache
• Crankiness or anxiety
• Hunger
• Dizziness or confusion
• Blurry vision
• Slurred speech
• Sweating
• Feeling jittery or shakiness
• Fast heartbeat
• Seizures

Dehydration. Wegovy may cause diarrhea, nausea, and vomiting which may lead to dehydration. Dehydration may cause kidney damage. If you have nausea, vomiting, or diarrhea, drink plenty of water, so that you do not get dehydrated. Call your health care provider right away if you have any of the following symptoms of kidney damage.

• Reduced need to pee
• Swelling in your feet, ankles, or legs
• Weakness or unusual tiredness
• Difficulty catching your breath or chest pain/pressure
• Confusion
• Nausea
• Seizures

Vision Changes (Diabetic Retinopathy). If you have diabetic retinopathy, your vision changes may get worse with Wegovy. Call your health care provider if you notice any of the following vision changes (new or getting worse).

• Loss of central vision, which is used to read or drive
• Not being able to see colors
• Blurry vision
• Holes or black spots in your vision
• Floaters, or small spots in your vision caused by bleeding

Fast Heart Rate (Tachycardia). Wegovy may cause your heart rate to increase. Call your health care provider right away if you feel like your heart is pounding or racing when you are not exerting yourself.

Suicidal Thoughts and Actions. Wegovy may cause suicidal thoughts or actions in a small number of people. If you are about to harm yourself, call 911 or call or text 988, the Suicide & Crisis Lifeline. Call your health care provider right away if you have any of the following symptoms.

• New or increased thoughts of suicide or death
• Suicide attempt
• New or increased feelings of anxiety, depression, or other unusual changes in mood or behavior

Wegovy Dosing Information

The starting Wegovy dose is 0.25 mg once a week for four weeks, and then your Wegovy dose will increase every 4 weeks until you reach a maintenance dose of 1.7 mg or 2.4 mg weekly. The Wegovy dosing schedule starts at a low dose and increases over months to reduce the risk of gastrointestinal side effects.  If patients do not tolerate a dose during dosage escalation, consider delaying dosage escalation for 4 weeks. 

Wegovy Dosing Schedule

Initial Wegovy Dose Escalation Schedule (all indications):

• Week 1 to 4: 0.25 mg once a week  
• Week 5 to 8: 0.5 mg once a week
• Weeks 9 to 12: 1 mg once a week
• Weeks 13 to 16: 1.7 mg once a week for(month four)

Maintenance Wegovy Dose (Cardiovascular Risk Reduction and Weight Reduction):

•  Week 17 and onward: 1.7 mg or 2.4 mg once a week

Maintenance Wegovy Dose (Non-cirrhotic MASH with Moderate to Advanced Liver Fibrosis):

• Week 17 and onward:  2.4 mg once a week from 
• If patients do not tolerate the maintenance dosage of 2.4 mg once weekly, the dosage can be decreased to 1.7 mg once weekly. Consider re-escalation to 2.4 mg once weekly.

What happens if I miss a dose?

• Use the medicine as soon as possible and then return to your regular schedule. But If your next dose is due in less than two days (48 hours), skip the missed dose and return to your regular schedule.
• Call your doctor if you miss more than two doses in a row of Wegovy. You may need to restart the medicine at a lower dose to avoid stomach problems.
• Do not use two doses of semaglutide at one time.

What happens if I overdose?

• Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
• Overdose may cause severe nausea, vomiting, or low blood sugar.

Storage 

Wegovy single-dose pen:

• Wegovy should be stored in refrigerator from 2°C to 8°C (36°F to 46°F). 
• If needed (prior to cap removal), the pen can be kept from 8°C to 30°C (46°F to 86°F) for up to 28 days. 
• Do not freeze. 
• Protect Wegovy from light, and it must be kept in the original carton until time of administration. Discard the Wegovy pen after use.